Kill 10 enemies with the Grenade Launcher in Multiplayer
Kill 150 enemies while using Power Ups.
Use a taunt from Expansion 2 during a Multiplayer Match
Unlock all Multiplayer Runes
Kill 10 enemies with the Reaper in Multiplayer
Earn a Gold Rating in a Multiplayer Match
Defeat the Spider Mastermind.
Complete the campaign on 'I'm Too Young to Die', 'Hurt Me Plenty', 'Ultra Violence', or 'Nightmare'.
Kill 50 enemies using the chainsaw.
Defeat the Hell Guards.
Earn the Mastery for a weapon mod.
Fully upgrade a Praetor Suit category.
Defeat the Cyberdemon.
Acquire the BFG.
Glory Kill all common enemy types in the campaign.
Perform 200 Glory Kills.
Warp to Hell.
Upgrade a Rune.
Detect 20 enemies using the Threat Pulse in Multiplayer
Win a Multiplayer match.
Reach Level 5 in Multiplayer.
Earn a Rune.
Complete the first mission of the campaign.
Play 5 published SnapMaps
Create and publish a SnapMap.
Complete the SnapMap Basic and Advanced Tutorials
Complete "The UAC" on Ultra-Nightmare.
Complete all Mission Challenges on a single campaign run.
Find all Collectibles.
Earn the Masteries for all weapon mods.
Upgrade all Runes.
Fully upgrade all Praetor Suit categories on a single campaign run.
Earn all Runes.
Use explosive barrels to kill 100 enemies.
Find all Data Logs.
Acquire all weapon mods.
Fully upgrade Health, Armor, and Ammo capacity on a single campaign run.
Fully upgrade Health, Armor, or Ammo capacity.
Complete all Challenges for a single mission.
Kill 10 enemies with the Harvester demon in Multiplayer
Kill 10 enemies with the EMG Mark V Pistol in Multiplayer
Kill 5 enemies with the Kinetic Mine in Multiplayer
Use a taunt from Expansion 1 during a Multiplayer Match
Play a Multiplayer Match with a piece of Robotic Armor equipped
Kill 10 enemies with the Cacodemon in Multiplayer
Play a Multiplayer Match with a piece of Cyber-Demonic armor equipped
Earn every medal type in Arcade Mode in one run
Earn a gold rating in Arcade Mode
Collect 20 bonus lives or relics in Arcade Mode
Kill 10 enemies with the Spectre demon in Multiplayer
Perform a MultiKill with the Spectre demon in Multiplayer
Use a taunt from Expansion 3 during a Multiplayer Match
Play a Multiplayer Match with a piece of Evil Cultist armor equipped
Complete a tracked Challenge in a Multiplayer Match